Question 1

Cyclic neutropenia is so named because this condition

Accepted Answer

A)   has more than one inheritance pattern.
B)   has environmental factors that participate in its cause.
C)   displays a decrease in the number of neutrophils that occur in cycles of 21 to 27 days.
D)   allows persons to carry a gene with a dominant effect without any clinical manifestations.

Question 2

Which clinical syndrome caused by gross chromosomal abnormalities is associated with bilateral cleft lip and palate, microphthalmia or anophthalmia, and polydactyly?

Accepted Answer

A)   Trisomy 13
B)   Trisomy 21
C)   Turner syndrome
D)   Klinefelter syndrome

Question 3

Murray-Puretic-Drescher syndrome is also known as

Accepted Answer

A)   cherubism.
B)   gingival fibromatosis with multiple hyaline fibromas.
C)   gingival fibromatosis with hypertrichosis, epilepsy, and mental retardation syndrome.
D)   Laband syndrome.

Question 4

Persons with cyclic neutropenia display a decrease in the number of which circulating cells?

Accepted Answer

A)   Chromosomes
B)   Neutrophils
C)   Phenotypes
D)   RNA B

Question 5

Radicular dentin dysplasia is characterized by teeth with _____ crowns and _____ roots.

Accepted Answer

A)   normal; normal
B)   normal; abnormal
C)   abnormal; normal
D)   abnormal; abnormal

Question 6

Primitive germ cells have _____ chromosomes and are termed _____.

Accepted Answer

A)   23; diploid
B)   46; haploid
C)   23; haploid
D)   46; diploid

Question 7

MATCHING
For each genetic definition below, select the corresponding genetic term from the list provided.
-Set of signs or symptoms occurring together

Accepted Answer

A)  Autosomes
B)  Gamete
C)  Locus
D)  Mutation
E)  PhenotypeF) Syndrome

Question 8

Euploid, polyploid, and aneuploid are all terms relating to a(n)  _____ of chromosomes.

Accepted Answer

A)   alteration in the structure
B)   abnormal rearrangement
C)   alteration in the number
D)   duplication C

Question 9

Which statement is true regarding gross chromosomal abnormalities involving alterations in the number of human chromosomes?

Accepted Answer

A)   Aneuploidy is a complete second set of chromosomes, meaning a total of 46.
B)   Polyploidy is any number of chromosomes that do not represent an exact multiple of the total chromosome complement.
C)   Euploidy is a complete second set of chromosomes, meaning a total of 46.
D)   Aneuploidy may be represented by trisomy and monosomy.

Question 10

During meiosis, if chromosomes crossing over do not separate and both migrate to the same cell, a germ cell with an extra chromosome results. What is the term to describe this occurrence?

Accepted Answer

A)   Nondisjunction
B)   Chiasmata
C)   Translation
D)   Alleles

Question 11

In addition to the development of the neurofibromas, what is the prominent clinical manifestation seen with a patient with von Recklinghausen disease?

Accepted Answer

A)   Café au lait pigmentation of the skin
B)   Spider-like telangiectases on the lips, eyelids, and nose
C)   Abnormally formed bones that fracture easily
D)   Blue sclera

Question 12

Which statement is true concerning hemophilia A?

Accepted Answer

A)   It is inherited as an X-linked dominant condition.
B)   It is inherited as a Y-linked recessive condition.
C)   All X chromosomes are abnormal in the female carrier.
D)   Female carriers tend to bleed more than usual after extraction of teeth or scaling and curettage.

Question 13

Which is true about making a karyotype?

Accepted Answer

A)   Arginine may be used to arrest the mitosis of leukocytes at metaphase.
B)   Colchicine may be used to arrest the mitosis of leukocytes at metaphase.
C)   Colchicine may be used to arrest the mitosis of red blood cells at anaphase.
D)   It is used to evaluate molecular abnormalities in chromosomes.

Question 14

MATCHING
For each genetic definition below, select the corresponding genetic term from the list provided.
-The observable appearance of an individual

Accepted Answer

A)  Autosomes
B)  Gamete
C)  Locus
D)  Mutation
E)  PhenotypeF) Syndrome E

Question 15

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided.
-Trisomy 21

Accepted Answer

A)  Characterized by multiple abnormalities in various organs
B)  Down syndrome as a result of nondisjunction
C)  Nondisjunction of the X chromosome in the paternal gamete
D)  Deletion on the short arm of chromosome 5
E)  Fertilized ovum has two X chromosomes plus a Y chromosome

Question 16

Which term describes less than the normal amount of hair?

Accepted Answer

A)   Hypoplastic
B)   Hypotrichosis
C)   Haploid
D)   Nondisjunction

Question 17

Which type of RNA carries the message for translation of DNA to ribosomes in the cytoplasm?

Accepted Answer

A)   mRNA
B)   tRNA
C)   rRNA
D)   hnRNA

Question 18

Which statement is true of oogenesis?

Accepted Answer

A)   Oogenesis starts around the time of puberty.
B)   The second meiosis is completed at the beginning of ovulation.
C)   Nondisjunction is more prevalent in male spermatogenesis than in female oogenesis.
D)   The older the woman, the greater the chance of shedding a trisomic ovum.

Question 19

During translation

Accepted Answer

A)   polypeptides form an amino acid, and one or more amino acids form a protein.
B)   amino acids form a polypeptide, and one or more polypeptides form a protein.
C)   proteins form a polypeptide, and one or more polypeptides form an amino acid.
D)   amino acids form a protein, and one or more proteins form a polypeptide.

Question 20

The basic defect responsible for osteogenesis imperfecta is produced by various mutations affecting the genes that encode type I collagen, resulting in

Accepted Answer

A)   lack of otic ossicles.
B)   unilateral or bilateral aplasia or hypoplasia of clavicles.
C)   overgrowth of cortical bone in the midline of the palate.
D)   abnormally formed bones that fracture easily.

Exam 6: Genetics

Cyclic neutropenia is so named because this condition

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Which clinical syndrome caused by gross chromosomal abnormalities is associated with bilateral cleft lip and palate, microphthalmia or anophthalmia, and polydactyly?

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Murray-Puretic-Drescher syndrome is also known as

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Persons with cyclic neutropenia display a decrease in the number of which circulating cells?

Correct AnswerverifiedB

Radicular dentin dysplasia is characterized by teeth with _____ crowns and _____ roots.

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Primitive germ cells have _____ chromosomes and are termed _____.

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MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -Set of signs or symptoms occurring together

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Euploid, polyploid, and aneuploid are all terms relating to a(n) _____ of chromosomes.

Correct AnswerverifiedC

Which statement is true regarding gross chromosomal abnormalities involving alterations in the number of human chromosomes?

Correct AnswerverifiedShow Answer

During meiosis, if chromosomes crossing over do not separate and both migrate to the same cell, a germ cell with an extra chromosome results. What is the term to describe this occurrence?

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In addition to the development of the neurofibromas, what is the prominent clinical manifestation seen with a patient with von Recklinghausen disease?

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Which statement is true concerning hemophilia A?

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Which is true about making a karyotype?

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MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -The observable appearance of an individual

Correct AnswerverifiedE

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Trisomy 21

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Which term describes less than the normal amount of hair?

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Which type of RNA carries the message for translation of DNA to ribosomes in the cytoplasm?

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Which statement is true of oogenesis?

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During translation

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The basic defect responsible for osteogenesis imperfecta is produced by various mutations affecting the genes that encode type I collagen, resulting in

Correct AnswerverifiedShow Answer

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B

Radicular dentin dysplasia is characterized by teeth with _ crowns and _ roots.

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Primitive germ cells have _ chromosomes and are termed _.

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C

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E

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