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T4 and T3 are __________ hormones that are mainly transported __________ in the blood.


A) monoamine;bound to thyroxine-binding globulin (TBG)
B) monoamine;unbound (free)
C) steroid;bound to transcortin-binding protein (TBP)
D) steroid;unbound (free)
E) catecholamine;bound to thyroxine-binding globulin (TBG)

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Hormones serve as intracellular messengers.

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The initial response to stress is called the _________ and is mediated mainly by __________.


A) resistance stage;cortisol
B) resistance stage;aldosterone and cortisol
C) alarm reaction;norepinephrine and epinephrine
D) alarm reaction;cortisol
E) exhaustion stage;norepinephrine and epinephrine

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Which of the following is not a cause of Cushing syndrome?


A) ACTH hypersecretion by the pituitary
B) ACTH-secreting tumors
C) Hyperactivity of the adrenal cortex
D) Hyperactivity of the adrenal medulla
E) Excess cortisol secretion

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The ___________ can be found as part of the epithalamus,near the superior colliculi of the midbrain.


A) hypothalamus
B) pituitary gland
C) pineal gland
D) hypophysis
E) adrenal gland

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Which of the following is not a role of prostaglandins?


A) To induce labor contractions
B) To stop fever and pain
C) To constrict or dilate arterioles
D) To act as vasodilators or vasoconstrictors
E) To inhibit gastric secretion

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Peptide hormones are synthesized by cytoplasmic ribosomes as active enzymes.

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Which of the following is true regarding endocrine glands?


A) They secrete substances that do not alter the metabolism of their target cells,but have extracellular effects.
B) They secrete their products by way of ducts.
C) They have an unusually low density of blood capillaries.
D) They release their secretions into the blood.
E) Their secretions may be released onto the body surface.

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Myxedema is characterized by low metabolic rate,sluggishness,and sleepiness.

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The exhaustion stage of the general adaptation syndrome (stress response)sets in only if protein reserves are depleted.

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Which of the following is the correct sequence of events leading to the polyuria and dehydration associated with diabetes mellitus?


A) Hyperglycemia → glucose in urine raises osmolarity of tubular fluid → glucose transport maximum exceeded → glucose enters renal tubules → osmotic diuresis
B) Hyperglycemia → glucose enters renal tubules → glucose transport maximum exceeded → glucose in urine raises osmolarity of tubular fluid → osmotic diuresis
C) Hyperglycemia → glucose enters renal tubules → glucose in urine raises osmolarity of tubular fluid → osmotic diuresis → glucose transport maximum exceeded
D) Hyperglycemia → glucose transport maximum exceeded → glucose enters renal tubules → glucose in urine raises osmolarity of tubular fluid → osmotic diuresis
E) Osmotic diuresis → glucose enters renal tubules → glucose transport maximum exceeded → glucose in urine raises osmolarity of tubular fluid → hyperglycemia

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Any situation that upsets homeostasis and threatens one's physical or emotional well-being is called __________.


A) stress
B) pathology
C) disease
D) hyperthyroidism
E) hirsuitism

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The __________ secretes a hormone that increases the body's metabolic rate,promotes alertness,quickens reflexes,and stimulates the fetal nervous system.


A) thyroid gland
B) pancreas
C) adrenal gland
D) parathyroid gland
E) thymus

Correct Answer

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During the exhaustion stage of the general adaptation syndrome (stress response) ,stress overwhelms homeostasis.One characteristic of this stage is that __________.


A) glycogen supplies are depleted
B) energy demands are met primarily by fat metabolism
C) fermentation is not enough to provide the necessary ATP
D) energy demands are met primarily by protein metabolism
E) energy demands are met primarily by carbohydrate metabolism

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The _________ secretes growth hormone,which is also known as somatotropin.


A) posterior pituitary
B) anterior pituitary
C) hypothalamus
D) thyroid
E) thymus

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Which of the following organs has both endocrine and exocrine functions?


A) The adrenal gland
B) The salivary glands
C) The ovary
D) The pineal gland
E) The thymus

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The absence of iodine in the diet leads to __________.


A) hypoparathyroidism
B) hypothyroidism
C) hypocalcemia
D) hypoglycemia
E) hypoxemia

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Hormones are normally secreted via ducts into the bloodstream.

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Of the following hormones,which has more target cells in the body than the others?


A) Antidiuretic hormone (ADH)
B) Corticotropin releasing hormone (CRH)
C) Growth hormone-releasing hormone (GHRH)
D) Growth hormone (GH)
E) Oxytocin (OT)

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Which of the following makes it possible for even a small quantity of hormone to have a strong effect on its target cell?


A) Negative feedback inhibition
B) The antagonistic effect
C) Up-regulation
D) Enzyme amplification
E) Down-regulation

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