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The hypothesis that predicts no linkage between genes is known as the null hypothesis.

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If an individual is heterozygous at two loci (Ab/aB) which are on the same chromosome arm with the A locus closest the centromere under what conditions would a crossover in a somatic cell generate a twin spot?


A) The crossover would have to occur between the A locus and the centromere locus and involve two homologous (non-sister) chromatids.
B) The crossover would have to occur between the A locus and the B locus and involve two homologous (non-sister) chromatids.
C) The crossover would have to occur between the B locus and the end of the chromosome locus and involve two homologous (non-sister) chromatids.
D) A double crossover would have to occur, with one crossover between the A locus and the centromere and a second crossover between the A and B loci locus and both crossovers would have to involve two homologous (non-sister) chromatids.
E) No crossover in a somatic cell could generate a twin spot.

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Chiasmata are structures of cross over between sister chromatids of homologous chromosomes.

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Calculate the coefficient of coincidence in this region.


A) 0
B) 0.16
C) 0.33
D) 0.5
E) 0.66

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Genes Q and R are 20 map units apart.If a plant of genotype QR / qr is selfed, what percentage of the progeny will be qr in phenotype?


A) 4%
B) 10%
C) 16%
D) 20%
E) 40%

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ws; ws; ws+; ws+; ws; ws; ws+; ws+


A) First-division segregation pattern
B) Second-division segregation pattern

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The measured distance between genes D and E in a two point test cross is 50 map units.What does this mean in physical terms?


A) D and E are on different pairs of chromosomes.
B) D and E are linked and exactly 50 map units apart.
C) D and E are linked and at least 50 map units apart.
D) either D and E are on different pairs of chromosomes or D and E are linked and exactly 50 map units apart
E) either D and E are on different pairs of chromosomes or D and E are linked and at least 50 map units apart

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The R/r and S/s genes are linked and 10 map units apart.In the cross Rs/rS * rs/rs what fraction of the progeny will be RS/rs?


A) 5%
B) 10%
C) 25%
D) 40%
E) 45%

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How many degrees of freedom are there?


A) 1
B) 2
C) 3
D) 4

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Which classes are the parental types?


A) wild-type and orange
B) brown and bright-red
C) wild-type and brown
D) bright-red and orange
E) There is no way to determine this.

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Sturtevant's detailed mapping studies of the X chromosome of Drosophila established what genetic principle?


A) That genes are arranged in a linear order on the chromosomes.
B) That genes are carried on chromosomes.
C) That sex determination is controlled by the X and Y chromosomes.
D) That segregation of an allelic gene pair is accompanied by disjunction of homologous chromosomes.
E) That different pairs of chromosomes assort independently.

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A female mouse from a true-breeding wild-type strain was crossed to a male mouse with apricot eyes (ap) and grey body (gy) .The F1 mice were wild-type for both traits.When the F1 were interbred, the F2 were distributed as follows: A female mouse from a true-breeding wild-type strain was crossed to a male mouse with apricot eyes (ap)  and grey body (gy) .The F<sub>1</sub> mice were wild-type for both traits.When the F<sub>1</sub> were interbred, the F<sub>2</sub> were distributed as follows:   Which of the following statements is correct? A) ap and gy are unlinked. B) ap and gy are linked on an autosome and 10 map units apart. C) ap and gy are linked on an autosome and 20 map units apart. D) ap and gy are X-linked and 10 map units apart. E) ap and gy are X-linked and 20 map units apart. Which of the following statements is correct?


A) ap and gy are unlinked.
B) ap and gy are linked on an autosome and 10 map units apart.
C) ap and gy are linked on an autosome and 20 map units apart.
D) ap and gy are X-linked and 10 map units apart.
E) ap and gy are X-linked and 20 map units apart.

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In ascomycete fungi, the arrangement of the spores in the ascus that directly reflects the order in which they were produced during meiosis is called an ______.


A) Unordered tetrad
B) Unordered octad
C) Ordered tetrad
D) Ordered pentad

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A crossover that would result in genetic recombination (e.g., Abc or aBC) could involve which chromatids?


A) 1 & 2 or 3 & 4
B) 1 & 3 or 2 & 4
C) 1 & 4 or 2 & 3
D) 1 & 3 or 1 & 4 or 2 & 3 or 2 & 4
E) any two of the four chromatids

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If two or more of the genes are linked, what map distance separates them?


A) 4 mu
B) 12 mu
C) 24 mu
D) 50 mu
E) None of the genes are linked to each other.

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The zipper-like connection between paired homologs in early prophase is known as a


A) spindle fiber.
B) synaptic junction.
C) synaptonemal complex.
D) chiasma.
E) none of the choices are correct.

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In tetrad analysis, second-division segregations result from


A) single crossovers between linked genes.
B) double crossovers between linked genes.
C) single crossovers between a gene and a centromere.
D) independent assortment of unlinked genes.
E) nondisjunction of homologs.

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What is the genotype of the tall, red, wide-leaved parent?


A) Tt Rr Ww
B) Tt Rr WW
C) TT RR WW
D) TT Rr Ww
E) TT RR Ww

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Suppose a woman has four sons, and two are colorblind but have normal blood clotting and two have hemophilia but normal color vision.What is the probable genotype of the woman?


A) HR / hr
B) Hr / hr
C) hr / hR
D) Hr / hR
E) HR / Hr

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A coefficient of coincidence of 0.5 in a region of three genes means that half as many double crossovers were observed as would have been expected if crossovers in the two intervals were independent.

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