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The factor(s) that determine the duration of a twitch in various types of fibers is the speed of the


A) removal of Ca2+ ions from the sarcoplasm only.
B) hydrolysis of ATP only.
C) movement of Na+ across their membranes only.
D) removal of Ca2+ ions from the sarcoplasm and hydrolysis of ATP.
E) removal of Ca2+ ions from the sarcoplasm and hydrolysis of ATP and movement of Na+ across their membranes.

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Match the structures with the accurate description. -a single muscle cell


A) muscle fiber
B) fascicle
C) sarcolemma
D) myofibril
E) t-tubules

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Most of the time,the parallel thick and thin filaments of the myofibrils are connected by ________ that span the space between myosin and actin molecules.


A) tropomyosin molecules
B) crossbridges
C) nebulin molecules
D) sarcomeres
E) calcium ions

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For antagonistic muscle groups to move a limb,flexor contraction occurs coincident with


A) contraction of the extensor.
B) relaxation of the extensor.
C) no changes in the extensor.
D) contraction of the tendon.

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Which of the following is NOT a correct comparison of cardiac myocytes to other muscle cell types?


A) Like smooth muscle cells, some cardiac myocytes have pacemaker potentials.
B) Like some smooth muscle cells, cardiac myocytes are electrically coupled.
C) Like skeletal muscle cells, actin and myosin are organized into sarcomeres.
D) Like skeletal muscle, contraction of cardiac muscle is under autonomic nervous control.
E) Like smooth muscle cells, cardiac muscle is under hormonal control.

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During heavy exercise,the ATP requirements of active muscle are likely to be met by metabolism of


A) protein.
B) fatty acids.
C) carbohydrates.
D) nucleotides.

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The gap junctions in cardiac muscle are part of specialized cell junctions that are localized to the ________.

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In order for high force crossbridges to form in contracting skeletal muscle,calcium must


A) bind to calmodulin to phosphorylate the myosin.
B) phosphorylate the tropomyosin which moves it.
C) phosphorylate the troponin to move the tropomyosin.
D) bind to tropomyosin which moves the troponin.
E) bind to troponin which moves the tropomyosin.

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The interaction between Ca2+ and calmodulin in smooth muscle cells has been described as a second messenger system.Develop an argument to support this position,using another second messenger system you have studied for comparison.

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Ca2+ forms a complex with calmodulin.This ...

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Asynchronous activation of motor units is important because it functions to ________.

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The function of transverse tubules is to


A) store Ca2+ ions inside the muscle fiber.
B) rapidly conduct action potentials to the interior of the muscle fiber.
C) ensure a supply of glycogen throughout the muscle sarcoplasm.
D) conduct ATP molecules out of the mitochondria throughout the sarcoplasm.

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When comparing complete tetanus with unfused (incomplete) tetanus,which is true?


A) Complete tetanus involves some relaxation between twitches.
B) Complete tetanus involves development of maximum tension.
C) Complete tetanus occurs at a lower frequency of stimulation than unfused tetanus.
D) Complete tetanus would occur when there is more time between twitch contractions.

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Each myosin head has a binding site for


A) calcium only.
B) actin only.
C) ATP only.
D) calcium and ATP.
E) actin and ATP.

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In order for the bicep muscle to shorten,the force applied by the muscle must be ________ the load applied at the hand.


A) greater than
B) less than
C) equal to

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The tension generated in a skeletal muscle fiber is directly proportional to the number of


A) thick and thin filaments present.
B) nebulin and titin molecules present.
C) high energy crossbridges formed.
D) low energy crossbridges formed.
E) active sarcomeres.

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C

What are the three types of muscle tissues in the human body? What are the two common functions of muscles?

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Three types of tissues are ske...

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________ is composed of multiple globular molecules polymerized to form long chains or filaments.


A) Actin
B) Tropomyosin
C) Troponin
D) Myosin
E) Titin

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A flexor is a skeletal muscle whose shortening moves attached bones


A) away from one another.
B) towards one another.
C) medially
D) laterally.

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B

The hydrolysis of ATP causes myosin to immediately


A) swivel, moving the actin molecule.
B) release of ADP.
C) release from the actin.
D) rotate into a position (cocked) to bind to actin.
E) bind more tightly to the actin (rigor) .

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D

Describe the muscle condition called tetanus.Is this a normal or a pathological event? If it is normal,what is the function? If it is pathological,what is the cause? The bacterium Clostridium tetani causes a disease called tetanus or lockjaw; you may have been vaccinated against tetanus,especially if you ever had hospital treatment for a skin wound.Speculate on whether or not the name of this disease is related to the muscle condition and why the disease can be fatal.

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Tetanus is a state of maintained contrac...

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