Question 1

Silent mutations are possible due to the degenerate nature of the genetic code.

Accepted Answer

A) True 
 B)False

Question 2

The most common genotype in a population is called the mutant genotype.

Accepted Answer

A) True 
 B)False

Question 3

A translocation that moves a gene from an area of euchromatin to heterochromatin would typically cause a(n)  _______ in the expression of the gene.

Accepted Answer

A)  Reduction
B)  Increase
C)  Gene expression would remain the same

Question 4

HRR usually uses a sister chromatid.

Accepted Answer

A) True 
 B)False

Question 5

A sample of water is tested for mutagens. The water is subjected to a process known as high pressure liquid chromatography which can separate compounds based on their different biochemical properties. As material leaves the HPLC column its absorbance is measured at UV light which is used to detect a variety of different compounds. These readings were recorded as a trace on a graph (top chart in the figure) . Fractions from the column are collected and then tested in an Ames assay (bottom chart in the figure) . In this assay there were 900 colonies with the solvent alone control. Which fractions contain mutagens?

Accepted Answer

A)   7 and 16
B)   3 and 10
C)   3, 7, 10, and 16
D)   None of these fractions appear to contain a mutagen

Question 6

TNRE repeats frequently result in the addition of extra histidine amino acids to the protein.

Accepted Answer

A) True 
 B)False

Question 7

An example of a suppressor mutation would be

Accepted Answer

A)  An intragenic mutation that restores the inactive protein's structure
B)  An intergenic mutation that increases the activity of a protein performing a different function as the mutated protein
C)  An intergenic mutation that activates a transcription factor that increases the espression of a normal protein
D)  A mutation that suppresses cell growth

Question 8

Which types of mutations are least likely to be subjected to natural selection?

Accepted Answer

A)  Silent
B)  Missense
C)  Nonsense
D)  Insertion

Question 9

Breakpoints in chromosome can lead to mutant phenotypes when they occur in the middle of a gene.

Accepted Answer

A) True 
 B)False

Question 10

Mutations that change the configuration of a protein at a specific temperature are called ____ mutations.

Accepted Answer

A)  Neutral
B)  Beneficial
C)  Deleterious
D)  Conditional

Question 11

A heritable change in the genetic material is called a mutation.

Accepted Answer

A) True 
 B)False  True

Question 12

How does position effect influence gene expression?

Accepted Answer

A)   Point mutations in promoters frequently occur by this mechanism
B)   Translocations may result in a promoter that is normally used for one gene now controlling an entirely different gene.
C)   Since this mechanism relies on recombination it relies on the positioning of one allele so that it is under the control of the other allele.
D)   Translocations always result in a gene being recombined into an area of heterochromatin. B

Question 13

An example of a base analog would be

Accepted Answer

A)  EMS
B)  Nitrous acid
C)  5BU
D)  Nitrogen mustards
E)  Acridine dyes

Question 14

A temporary change in the conformation of a nitrogenous base is called ______.

Accepted Answer

A)  Depurination
B)  A tautomeric shift
C)  Deamination
D)  None of the answers are correct

Question 15

A mutation in a promoter region that causes the promoter sequence to more closely resemble the consensus sequence is called an up promoter mutation and results in a decrease in transcription.

Accepted Answer

A) True 
 B)False

Question 16

A change in the chromosome number is called a point mutation.

Accepted Answer

A) True 
 B)False

Question 17

The conversion of cytosine to uracil in DNA is an example of _____.

Accepted Answer

A)  Depurination
B)  Tautomeric shifts
C)  Deamination
D)  Demethylation

Question 18

Which repair mechanism utilizes MutL, MutH, and MutS proteins in

Accepted Answer

A)  Recombinational repair
B)  Direct repair
C)  Base excision repair
D)  Mismatch repair
E)  Nucleotide excision repairF)  Nonhomologous end joining (NHEJ)

Question 19

Spontaneous mutations include

Accepted Answer

A)  Depurination, deamination, errors in DNA replication
B)  UV light, radiation, deamination, depurination
C)  UV light, radiation, deamination, errors in replication
D)  UV light, errors in DNA replication, deamination, depurination

Question 20

Which is not an example of a induced mutational mechanism?

Accepted Answer

A)  DNA replication errors
B)  Tautomeric shifts of nucleic acid bases
C)  Aberrant recombination
D)  UV light
E)  Transposable elements D

Exam 18: Gene Mutation and Dna Repair

Silent mutations are possible due to the degenerate nature of the genetic code.

Correct Answer
verified

The most common genotype in a population is called the mutant genotype.

Correct Answer
verified

A translocation that moves a gene from an area of euchromatin to heterochromatin would typically cause a(n) _______ in the expression of the gene.

Correct Answer
verified

HRR usually uses a sister chromatid.

Correct Answer
verified

Correct Answer
verified

TNRE repeats frequently result in the addition of extra histidine amino acids to the protein.

Correct Answer
verified

An example of a suppressor mutation would be

Correct Answer
verified

Which types of mutations are least likely to be subjected to natural selection?

Correct Answer
verified

Breakpoints in chromosome can lead to mutant phenotypes when they occur in the middle of a gene.

Correct Answer
verified

Mutations that change the configuration of a protein at a specific temperature are called ____ mutations.

Correct Answer
verified

A heritable change in the genetic material is called a mutation.

Correct Answer
verified
True

How does position effect influence gene expression?

Correct Answer
verified
B

An example of a base analog would be

Correct Answer
verified

A temporary change in the conformation of a nitrogenous base is called ______.

Correct Answer
verified

A mutation in a promoter region that causes the promoter sequence to more closely resemble the consensus sequence is called an up promoter mutation and results in a decrease in transcription.

Correct Answer
verified

A change in the chromosome number is called a point mutation.

Correct Answer
verified

The conversion of cytosine to uracil in DNA is an example of _____.

Correct Answer
verified

Which repair mechanism utilizes MutL, MutH, and MutS proteins in

Correct Answer
verified

Spontaneous mutations include

Correct Answer
verified

Which is not an example of a induced mutational mechanism?

Correct Answer
verified
D

Exam 18: Gene Mutation and Dna Repair

Silent mutations are possible due to the degenerate nature of the genetic code.

Correct AnswerverifiedShow Answer

The most common genotype in a population is called the mutant genotype.

Correct AnswerverifiedShow Answer

A translocation that moves a gene from an area of euchromatin to heterochromatin would typically cause a(n) _______ in the expression of the gene.

Correct AnswerverifiedShow Answer

HRR usually uses a sister chromatid.

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

TNRE repeats frequently result in the addition of extra histidine amino acids to the protein.

Correct AnswerverifiedShow Answer

An example of a suppressor mutation would be

Correct AnswerverifiedShow Answer

Which types of mutations are least likely to be subjected to natural selection?

Correct AnswerverifiedShow Answer

Breakpoints in chromosome can lead to mutant phenotypes when they occur in the middle of a gene.

Correct AnswerverifiedShow Answer

Mutations that change the configuration of a protein at a specific temperature are called ____ mutations.

Correct AnswerverifiedShow Answer

A heritable change in the genetic material is called a mutation.

Correct AnswerverifiedTrue

How does position effect influence gene expression?

Correct AnswerverifiedB

An example of a base analog would be

Correct AnswerverifiedShow Answer

A temporary change in the conformation of a nitrogenous base is called ______.

Correct AnswerverifiedShow Answer

A mutation in a promoter region that causes the promoter sequence to more closely resemble the consensus sequence is called an up promoter mutation and results in a decrease in transcription.

Correct AnswerverifiedShow Answer

A change in the chromosome number is called a point mutation.

Correct AnswerverifiedShow Answer

The conversion of cytosine to uracil in DNA is an example of _____.

Correct AnswerverifiedShow Answer

Which repair mechanism utilizes MutL, MutH, and MutS proteins in

Correct AnswerverifiedShow Answer

Spontaneous mutations include

Correct AnswerverifiedShow Answer

Which is not an example of a induced mutational mechanism?

Correct AnswerverifiedD

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True

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B

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D