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Which of the following statements is TRUE?


A) Complement activity is antigen-specific.
B) Complement increases after immunization.
C) All of the complement proteins are constantly active in serum.
D) There are at least thirty complement proteins.
E) Factors B, D, and P cause cytolysis.

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Macrophages arise from which of the following?


A) eosinophils
B) neutrophils
C) monocytes
D) basophils
E) lymphocytes

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All of the following are components of the inflammatory process EXCEPT


A) diapedesis.
B) chemotaxis.
C) dilation of blood vessels.
D) release of histamines and prostaglandins.
E) antibody synthesis.

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Which of the following statements about fixed macrophages is FALSE?


A) They are mature monocytes.
B) They gather at sites of infection.
C) They are cells of the mononuclear phagocytic system.
D) They develop from neutrophils.
E) They are found in certain tissues and organs.

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A child falls and suffers a deep cut on her leg. The cut went through her skin and she is bleeding. Which of the following defense mechanisms will participate in eliminating contaminating microbes?


A) normal skin flora
B) lysozyme
C) acidic skin secretions
D) mucociliary escalator
E) phagocytosis in the inflammatory response

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Activation of C3a results in


A) opsonization.
B) acute inflammation.
C) attraction of phagocytes.
D) increased blood vessel permeability.
E) cell lysis.

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After ingesting a pathogen, lysosomal enzymes produce all of the following EXCEPT


A) complement.
B) HOCl.
C) Oâ‚‚-.
D) Hâ‚‚Oâ‚‚.
E) OH.

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The lectin pathway for complement action is initiated by


A) mannose on the surface of microbes.
B) gram-negative cell walls.
C) mannose on host membranes.
D) gram-positive cell walls.
E) lectins of the microbe.

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Normal microbiota provide protection from infection in each of the following ways EXCEPT


A) they make the chemical environment unsuitable for nonresident bacteria.
B) they produce antibacterial chemicals.
C) they produce lysozyme.
D) they change the pH of the environment.
E) they compete with pathogens for nutrients.

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Margination refers to


A) adherence of phagocytes to the lining of blood vessels.
B) the adherence of phagocytes to microorganisms.
C) the chemotactic response of phagocytes.
D) dilation of blood vessels.
E) the movement of phagocytes through walls of blood vessels.

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Aspirin alleviates pain, inflammation, and fever by inhibiting prostaglandins.

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Complement proteins in their intact and unactivated form act as opsonins by binding to microorganisms and promoting phagocytosis.

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Phagocytes utilize all of the following to optimize interaction with (getting to and getting hold of) microorganisms EXCEPT


A) chemotaxis.
B) complement.
C) trapping a bacterium against a rough surface.
D) opsonization.
E) lysozyme.

Correct Answer

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