Question 1

The mechanism of action of interferon includes all of the following except

Accepted Answer

A)   It works in cells not producing INF.
B)   It initiates manufacture of another antiviral protein.
C)   It binds to the surface of uninfected cells.
D)   It inactivates viruses.
E)   None of the above.

Question 2

Which of the following does not provide protection from phagocytic digestion?

Accepted Answer

A)   Lysing phagolysosomes
B)   Killing white blood cells
C)   Ability to grow at a low pH
D)   Preventing formation of phagolysosomes
E)   None of the above

Question 3

Which of the following does not cause vasodilation?

Accepted Answer

A)   Kinins
B)   Lysozymes
C)   Prostaglandins
D)   Histamine
E)   None of the above

Question 4

Chlamydia trachomatis can live inside white blood cells because it

Accepted Answer

A)   Prevents complement activation.
B)   Inhibits phagocytosis.
C)   Inhibits formation of phagolysosomes.
D)   Produces keratinase.
E)   Produces complement. C

Question 5

"Margination" refers to

Accepted Answer

A)   Adherence of phagocytes to the lining of blood vessels.
B)   The chemotactic response of phagocytes.
C)   Dilation of blood vessels.
D)   The adherence of phagocytes to microorganisms.
E)   The movement of phagocytes through walls of blood vessels.

Question 6

After ingesting a pathogen, lysosomal enzymes produce all of the following except

Accepted Answer

A)   O₂- .
B)   Complement.
C)   HOCl.
D)   H₂O₂.
E)   OH·.

Question 7

The function of the "ciliary escalator" is to

Accepted Answer

A)   Kill microorganisms.
B)   Remove microorganisms from body cavities.
C)   Remove microorganisms from the upper respiratory tract.
D)   Remove microorganisms from the lower respiratory tract.
E)   All of the above.

Question 8

Which of the following is not an effect of complement activation?

Accepted Answer

A)   Opsonization
B)   Increased phagocytic activity
C)   Interference with viral replication
D)   Increased blood vessel permeability
E)   Bacterial cell lysis

Question 9

The classical pathway for complement activation is initiated by

Accepted Answer

A)   Antigen- antibody reactions.
B)   Factors released from damaged tissues.
C)   Polysaccharides and C₃b.
D)   C₅- C9.
E)   Factors released from phagocytes.

Question 10

Which of the following is not true of fixed macrophages?

Accepted Answer

A)   They develop from neutrophils.
B)   They are found in certain tissues and organs.
C)   They are mature monocytes.
D)   They are cells of the mononuclear phagocytic system.
E)   None of the above.

Question 11

Which of the following is not a characteristic of inflammation?

Accepted Answer

A)   Swelling
B)   Pain
C)   Fever
D)   Redness
E)   Local heat

Question 12

Which of the following is not true about the classical pathway of complement activation?

Accepted Answer

A)   C₃ is not involved in the classical pathway.
B)   C₁ is the first protein activated in the classical pathway.
C)   Cleaved fragments of some of the proteins act to increase inflammation.
D)   C₃b causes opsonization.
E)   The C₁ protein complex is initiated by antigen- antibody complexes.

Question 13

Which of the following is involved in adaptive immunity?

Accepted Answer

A)   Lymphocyte
B)   Monocyte
C)   Neutrophil
D)   Eosinophil
E)   Basophil A

Question 14

Activation of C₃a results in all of the following except

Accepted Answer

A)   Increased blood vessel permeability.
B)   Attraction of phagocytes.
C)   Fever.
D)   Acute inflammation.
E)   None of the above.

Question 15

Adherence of phagocytes may be accomplished by all of the following except

Accepted Answer

A)   Trapping a bacterium against a rough surface.
B)   Lysozyme.
C)   Opsonization.
D)   Chemotaxis.
E)   Complement.

Question 16

The lectin pathway for complement action is initiated by

Accepted Answer

A)   Lectins of the parasite.
B)   Mannose on host membranes.
C)   Gram- negative cell walls.
D)   Mannose on the parasite.
E)   None of the above.

Question 17

Bacteria have siderophores that capture iron; humans counter this by

Accepted Answer

A)   Transferrins.
B)   Toxin production.
C)   Iron- degrading enzymes.
D)   Producing iron.
E)   None of the above.

Question 18

Which of the following is not an effect of histamine?

Accepted Answer

A)   Fever
B)   Vasodilation
C)   Pain
D)   Redness
E)   Swelling

Question 19

Defensive cells such as T cells identify pathogens by binding:

Accepted Answer

A)   Lectins.
B)   Toll- like receptors.
C)   Lysozyme.
D)   Complement.
E)   Cytokines.

Question 20

Which of the following is involved in resistance to parasitic helminths?

Accepted Answer

A)   Lymphocyte
B)   Neutrophil
C)   Eosinophil
D)   Basophil
E)   Monocyte C

Exam 16: Innate Immunity: Nonspecific Defenses of the Host

The mechanism of action of interferon includes all of the following except

Correct AnswerverifiedShow Answer

Which of the following does not provide protection from phagocytic digestion?

Correct AnswerverifiedShow Answer

Which of the following does not cause vasodilation?

Correct AnswerverifiedShow Answer

Chlamydia trachomatis can live inside white blood cells because it

Correct AnswerverifiedC

"Margination" refers to

Correct AnswerverifiedShow Answer

After ingesting a pathogen, lysosomal enzymes produce all of the following except

Correct AnswerverifiedShow Answer

The function of the "ciliary escalator" is to

Correct AnswerverifiedShow Answer

Which of the following is not an effect of complement activation?

Correct AnswerverifiedShow Answer

The classical pathway for complement activation is initiated by

Correct AnswerverifiedShow Answer

Which of the following is not true of fixed macrophages?

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Which of the following is not a characteristic of inflammation?

Correct AnswerverifiedShow Answer

Which of the following is not true about the classical pathway of complement activation?

Correct AnswerverifiedShow Answer

Which of the following is involved in adaptive immunity?

Correct AnswerverifiedA

Activation of C₃a results in all of the following except

Correct AnswerverifiedShow Answer

Adherence of phagocytes may be accomplished by all of the following except

Correct AnswerverifiedShow Answer

The lectin pathway for complement action is initiated by

Correct AnswerverifiedShow Answer

Bacteria have siderophores that capture iron; humans counter this by

Correct AnswerverifiedShow Answer

Which of the following is not an effect of histamine?

Correct AnswerverifiedShow Answer

Defensive cells such as T cells identify pathogens by binding:

Correct AnswerverifiedShow Answer

Which of the following is involved in resistance to parasitic helminths?

Correct AnswerverifiedC

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A

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C