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Variolation is a procedure once used to protect against


A) measles.
B) bubonic plague.
C) rabies.
D) smallpox.

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Attenuated agents often give rise to a long-lasting immunity.

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A monoclonal antibody is typically IgE and recognizes several epitopes.

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The Salk vaccine


A) protects against nervous system and gastrointestinal infection.
B) protects only against gastrointestinal infection.
C) is a subunit vaccine.
D) protects only against nervous system infection.
E) protects against nervous system and gastrointestinal infection AND is a subunit vaccine.

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An adjuvant has been developed from Lipid A.

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Attenuated agents


A) may induce immunity after a single dose.
B) may cause disease in immunocompromised individuals.
C) multiply in the body.
D) may revert or mutate to disease-causing strains.
E) All of the choices are correct.

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A recombinant vaccine is used to protect against


A) polio.
B) diphtheria.
C) hepatitis B
D) pertussis.

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Inactivated immunizing agents are prepared by treatment with


A) alcohol.
B) phenol.
C) formalin.
D) histamine.

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DNA vaccines work by


A) stimulating production of antibodies against DNA.
B) stimulating interferon production.
C) inactivating the host DNA.
D) having the cell use the introduced DNA to make the microbial protein antigen.

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Agglutination tests can be used to diagnose diseases caused by


A) bacteria.
B) hormones.
C) fungi.
D) viruses.
E) All of the choices are correct.

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Since many childhood diseases such as mumps and measles are rare now within the US, why is it still important for children to be immunized against them?


A) If we lose herd immunity by removing mandatory vaccination, our population will become susceptible to these illnesses again in a short period of time.
B) There is always the likelihood that an individual from another country could import one of these illnesses into the US, sparking an outbreak of new infections, if we aren't all properly vaccinated.
C) By keeping the population vaccinated, we keep incidence rates of these illnesses very low.This helps to protect people that cannot be vaccinated (very young children, pregnant women, immunocompromised individuals, the elderly) .
D) Many of these diseases are HIGHLY contagious, and commonly through respiratory droplet (airborne) transmission.This makes an outbreak within a susceptible population very possible.Keeping the population resistant through mandatory vaccination prevents this possibility.
E) All of the options are correct.

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The virus originally used for vaccination against smallpox is named


A) vaccinia.
B) cowpox.
C) rubella.
D) herpes.

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The risk of serious illness from measles is 500 times greater than from vaccination against the disease.

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DNA vaccines are dangerous due to the possibility of the DNA causing reversion in the inactivated pathogen.

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Serological tests are most often conducted in


A) test tubes.
B) flasks.
C) microtiter plates.
D) graduated cylinders.

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Precipitation reactions depend on


A) the antigen having one epitope.
B) the antibody having one epitope.
C) the antigen having two or more epitopes.
D) the antigen having no epitopes.

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Monoclonal antibodies obtained from a hybridoma provide


A) a large amount of an antibody that is specific for a particular antigen.
B) a single antibody that recognizes many antigens.
C) many antigens that recognize a specific antibody.
D) a large number of B cells.

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The effectiveness of DNA vaccines stems from the effective production of antibodies against the naked DNA molecule.

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The practice of deliberately stimulating the immune system is called


A) acquired immunity.
B) memory immunity.
C) vaccination.
D) hypersensitivity.

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Substances that are contained in vaccines to help induce a better immune response are called


A) primary substances.
B) secondary substances.
C) adjuvants.
D) adjuncts.

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